THE SOFIA PILOT TRIAL: A CLUSTER-RANDOMIZED TRIAL OF COORDINATED, CO-PRODUCED CARE TO REDUCE MORTALITY AND IMPROVE QUALITY OF LIFE IN PEOPLE WITH SEVERE MENTAL ILLNESS IN THE GENERAL PRACTICE SETTING

Abstract Background People with severe mental illness (SMI) have an increased risk of premature mortality, predominantly due to somatic health conditions.Evidence indicates that primary and tertiary prevention and improved treatment of somatic conditions in patients with SMI could reduce this excess mortality.This paper reports a protocol designed

Most cosmetic products require preservation to prevent microbial contamination and to ensure consumer safety.Due to regulatory restrictions and rejection by consumers, preservative options Mirrorless Lens have become limited and the development of novel solutions is needed.This search can be guided by knowledge about favorable chemical space for co

Abstract Background Systemic racism in Canadian healthcare may be observed through racially inequitable outcomes, particularly for Indigenous people.Nursing approaches intending to respond to racism often focus on culture without critically addressing the roots of racist inequity directly.In contrast, the critical race theory approach used in this

Abstract Background Highly multiplexed imaging enables single-cell-resolved detection of numerous biological molecules in their spatial tissue context.Interactive visualization of multiplexed imaging data is crucial at any step of data analysis to facilitate quality control and the spatial exploration of single cell features.However, tools for inte